Trypanocidal activity of salinomycin is due to sodium influx followed by cell swelling

Dietmar Steverding, Darren W. Sexton

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

The few currently available drugs for treatment of African trypanosomiasis are outdated and show problems with toxicity and resistance. Hence, there is an urgent need for the discovery and development of new anti-trypanosomal agents.
Original languageEnglish
Article number78
JournalParasites & Vectors
Volume6
DOIs
Publication statusPublished - 21 Mar 2013

Keywords

  • Antiprotozoal Agents
  • Inhibitory Concentration 50
  • Osmotic Pressure
  • Pyrans
  • Sodium
  • Trypanosoma brucei brucei

Cite this