Turning the tide: A history and review of hyperhidrosis treatment

Kevin Y C Lee, Nick J Levell

Research output: Contribution to journalArticlepeer-review


Hyperhidrosis is a potential cause of severe physical and psychological distress, interfering in activities of daily living. Over the past 100 years, advances have been made regarding the treatment of this debilitating condition with some success. Surgical treatment with sympathectomy was successfully performed for hyperhidrosis in the early part of the 20th century, with various modifications of the technique over the past 100 years. Topical aluminium salt antiperspirants, anticholinergic medications, iontophoresis and botulinum toxin introduced less invasive ways to manage this condition. This historical review will enable dermatologists and non-dermatologists to manage this distressing condition.

Original languageEnglish
Pages (from-to)2042533313505511
JournalJRSM Open
Issue number1
Publication statusPublished - 7 Jan 2014
Externally publishedYes


  • Journal Article
  • Review

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