Two polymorphs of a beta-lactam (trans-13-azabicyclo[10.2.0]tetradecan-14-one). Concomitant crystal polymorphism and isostructurality

László Fábián; Alajos Kálmán; Gyula Argay; Gábor Bernáth; Zsuzsanna Cs. Gyarmati

doi:10.1039/b408505a

Two polymorphs of a beta-lactam (trans-13-azabicyclo[10.2.0]tetradecan-14-one). Concomitant crystal polymorphism and isostructurality

László Fábián, Alajos Kálmán, Gyula Argay, Gábor Bernáth, Zsuzsanna Cs. Gyarmati

Pharmaceutical Materials and Soft Matter

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

Two polymorphs of trans-13-azabicyclo[10.2.0] tetradecan-14-one display a unique example of isostructurality, differing only in the orientation of a given hydrogen bond with respect to the beta-lactam bond. This slight difference can be attributed to the twofold rotation of the carbocyclic macroring of C-2 symmetry, which in the crystal structure is hardly noticeable.

Original language	English
Pages (from-to)	2114-2115
Number of pages	2
Journal	Chemical Communications
Issue number	18
DOIs	https://doi.org/10.1039/b408505a
Publication status	Published - 3 Aug 2004

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10.1039/b408505a

Cite this

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AU - Kálmán, Alajos

AU - Argay, Gyula

AU - Bernáth, Gábor

AU - Gyarmati, Zsuzsanna Cs.

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