Two widely disseminated strains of Enterococcus faecalis highly resistant to gentamicin and ciprofloxacin from bacteraemias in the UK and Ireland

Neil Woodford; Rosy Reynolds; Jane Turton; Fiona Scott; Alistair Sinclair; Andrea Williams; David Livermore

doi:10.1093/jac/dkg408

Two widely disseminated strains of Enterococcus faecalis highly resistant to gentamicin and ciprofloxacin from bacteraemias in the UK and Ireland

Neil Woodford, Rosy Reynolds, Jane Turton, Fiona Scott, Alistair Sinclair, Andrea Williams, David Livermore

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

A strong association was observed between high-level resistance to ciprofloxacin and gentamicin for isolates of Enterococcus faecalis collected in the UK and Ireland as part of the BSAC Bacteraemia Resistance Surveillance Programme, 2001. Thus, 60 of 66 E. faecalis isolates with gentamicin MICs > or =512 mg/L were highly resistant to ciprofloxacin (MICs > or =32 mg/L), compared with only three of 83 E. faecalis isolates with normal gentamicin susceptibility (MICs

Original language	English
Pages (from-to)	711-4
Number of pages	4
Journal	Journal of Antimicrobial Chemotherapy
Volume	52
Issue number	4
DOIs	https://doi.org/10.1093/jac/dkg408
Publication status	Published - Oct 2003

Keywords

Bacteremia
Ciprofloxacin
Drug Resistance, Bacterial
Enterococcus faecalis
Gentamicins
Great Britain
Humans
Ireland

Access to Document

10.1093/jac/dkg408

Cite this

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title = "Two widely disseminated strains of Enterococcus faecalis highly resistant to gentamicin and ciprofloxacin from bacteraemias in the UK and Ireland",

abstract = "A strong association was observed between high-level resistance to ciprofloxacin and gentamicin for isolates of Enterococcus faecalis collected in the UK and Ireland as part of the BSAC Bacteraemia Resistance Surveillance Programme, 2001. Thus, 60 of 66 E. faecalis isolates with gentamicin MICs > or =512 mg/L were highly resistant to ciprofloxacin (MICs > or =32 mg/L), compared with only three of 83 E. faecalis isolates with normal gentamicin susceptibility (MICs ",

keywords = "Bacteremia, Ciprofloxacin, Drug Resistance, Bacterial, Enterococcus faecalis, Gentamicins, Great Britain, Humans, Ireland",

author = "Neil Woodford and Rosy Reynolds and Jane Turton and Fiona Scott and Alistair Sinclair and Andrea Williams and David Livermore",

year = "2003",

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doi = "10.1093/jac/dkg408",

language = "English",

volume = "52",

pages = "711--4",

journal = "Journal of Antimicrobial Chemotherapy",

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T1 - Two widely disseminated strains of Enterococcus faecalis highly resistant to gentamicin and ciprofloxacin from bacteraemias in the UK and Ireland

AU - Woodford, Neil

AU - Reynolds, Rosy

AU - Turton, Jane

AU - Scott, Fiona

AU - Sinclair, Alistair

AU - Williams, Andrea

AU - Livermore, David

PY - 2003/10

Y1 - 2003/10

N2 - A strong association was observed between high-level resistance to ciprofloxacin and gentamicin for isolates of Enterococcus faecalis collected in the UK and Ireland as part of the BSAC Bacteraemia Resistance Surveillance Programme, 2001. Thus, 60 of 66 E. faecalis isolates with gentamicin MICs > or =512 mg/L were highly resistant to ciprofloxacin (MICs > or =32 mg/L), compared with only three of 83 E. faecalis isolates with normal gentamicin susceptibility (MICs

AB - A strong association was observed between high-level resistance to ciprofloxacin and gentamicin for isolates of Enterococcus faecalis collected in the UK and Ireland as part of the BSAC Bacteraemia Resistance Surveillance Programme, 2001. Thus, 60 of 66 E. faecalis isolates with gentamicin MICs > or =512 mg/L were highly resistant to ciprofloxacin (MICs > or =32 mg/L), compared with only three of 83 E. faecalis isolates with normal gentamicin susceptibility (MICs

KW - Bacteremia

KW - Ciprofloxacin

KW - Drug Resistance, Bacterial

KW - Enterococcus faecalis

KW - Gentamicins

KW - Great Britain

KW - Humans

KW - Ireland

U2 - 10.1093/jac/dkg408

DO - 10.1093/jac/dkg408

M3 - Article

C2 - 12917231

VL - 52

SP - 711

EP - 714

JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

SN - 0305-7453

IS - 4

ER -