Abstract
The worldwide epidemic in type 2 diabetes has been associated with an increased diagnosis in young adults. This has lead to a rapid rise in the number of pregnancies complicated by type 2 diabetes. Studies have shown risk of serious adverse outcome, including congenital malformation and perinatal mortality, is the same, or increased, in type 2 diabetes compared to type 1 diabetes. Despite improved glycaemic control in type 2 diabetes compared to type 1 diabetes, rates of perinatal morbidity, including preterm birth and macrosomia, appear to be similar. Risk factors associated with poor pregnancy outcome in women with type 2 diabetes include obesity, ethnicity and poor pregnancy preparation. This review will cover practical aspects of management of type 2 diabetes before, during and after pregnancy, including prepregnancy care, safety of oral hypoglycaemic agents, glycaemic management during labour, and choice of effective contraception.
| Original language | English |
|---|---|
| Pages (from-to) | 591-603 |
| Number of pages | 13 |
| Journal | Best Practice and Research: Clinical Endocrinology & Metabolism |
| Volume | 24 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Aug 2010 |
Keywords
- type 2 diabetes
- prepregnancy care
- preconception
- obesity
- malformation
- perinatal mortality
