Type 2 diabetes in pregnancy: an increasing problem

Rosemary Temple, Helen Murphy

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The worldwide epidemic in type 2 diabetes has been associated with an increased diagnosis in young adults. This has lead to a rapid rise in the number of pregnancies complicated by type 2 diabetes. Studies have shown risk of serious adverse outcome, including congenital malformation and perinatal mortality, is the same, or increased, in type 2 diabetes compared to type 1 diabetes. Despite improved glycaemic control in type 2 diabetes compared to type 1 diabetes, rates of perinatal morbidity, including preterm birth and macrosomia, appear to be similar. Risk factors associated with poor pregnancy outcome in women with type 2 diabetes include obesity, ethnicity and poor pregnancy preparation. This review will cover practical aspects of management of type 2 diabetes before, during and after pregnancy, including prepregnancy care, safety of oral hypoglycaemic agents, glycaemic management during labour, and choice of effective contraception. 

Original languageEnglish
Pages (from-to)591-603
Number of pages13
JournalBest Practice and Research: Clinical Endocrinology & Metabolism
Volume24
Issue number4
DOIs
Publication statusPublished - Aug 2010

Keywords

  • type 2 diabetes
  • prepregnancy care
  • preconception
  • obesity
  • malformation
  • perinatal mortality

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