Understanding the use of sigma metrics in hemoglobin A1c analysis

Erna Lenters-Westra (Lead Author), Emma English

Research output: Contribution to journalArticlepeer-review

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This study utilizes three unique data sets to demonstrate the state of the art of HbA1c analyzers in a range of settings and compares their performance against the international guidance set by the IFCC task force for HbA1c standardization. The data is used to demonstrate the effect of tightening of those criteria and the study serves as a guide to the practical implementation of the sigma metrics approach in a range of clinical settings.
Original languageEnglish
Pages (from-to)57–71
Number of pages15
JournalClinics in Laboratory Medicine
Issue number1
Early online date14 Dec 2016
Publication statusPublished - Mar 2017


  • HbA1c
  • diabetes
  • sigma-metrics
  • analytical performance criteria

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