Up with categories, down with sets; Out with categories, in with sets!

Practical approaches to the notions of subsets and extension sets are compared, coming from broadly set-theoretic and category-theoretic traditions of mathematics. I argue that the set-theoretic approach is the most practical for “looking down” or “in” at subsets and the category-theoretic approach is the most practical for “looking up” or “out” at extensions, and suggest some guiding principles for using these approaches without recourse to either category theory or axiomatic set theory.