Vertebrate limb development - the early stages in chick and mouse

Cheryll Tickle; Andrea Münsterberg

doi:10.1016/S0959-437X(00)00220-3

Vertebrate limb development - the early stages in chick and mouse

Cheryll Tickle, Andrea Münsterberg

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Abstract

More news this year about FGFs and their roles in vertebrate limb initiation; Wnt signalling is shown for the first time to be another component of the signalling cascade involved in early limb formation. Ectodermal compartments that control apical ridge formation were previously described in chick embryos and are now shown to exist in mouse embryos; Engrailed1 is expressed in the ventral ectodermal compartment but experiments in both chick and mouse show that it is not responsible for compartment specification.

Original language	English
Pages (from-to)	476-481
Number of pages	6
Journal	Current Opinion in Genetics and Development
Volume	11
DOIs	https://doi.org/10.1016/S0959-437X(00)00220-3
Publication status	Published - 2001

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10.1016/S0959-437X(00)00220-3

01_Tickle_CurrentBiology_reviewSubmitted manuscript, 540 KB

Cite this

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title = "Vertebrate limb development - the early stages in chick and mouse",

abstract = "More news this year about FGFs and their roles in vertebrate limb initiation; Wnt signalling is shown for the first time to be another component of the signalling cascade involved in early limb formation. Ectodermal compartments that control apical ridge formation were previously described in chick embryos and are now shown to exist in mouse embryos; Engrailed1 is expressed in the ventral ectodermal compartment but experiments in both chick and mouse show that it is not responsible for compartment specification.",

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AB - More news this year about FGFs and their roles in vertebrate limb initiation; Wnt signalling is shown for the first time to be another component of the signalling cascade involved in early limb formation. Ectodermal compartments that control apical ridge formation were previously described in chick embryos and are now shown to exist in mouse embryos; Engrailed1 is expressed in the ventral ectodermal compartment but experiments in both chick and mouse show that it is not responsible for compartment specification.

U2 - 10.1016/S0959-437X(00)00220-3

DO - 10.1016/S0959-437X(00)00220-3

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JO - Current Opinion in Genetics and Development

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