Visual function and white matter microstructure in very-low-birth-weight (VLBW) adolescents--a DTI study

Susanne Lindqvist; Jon Skranes; Live Eikenes; Olav Haraldseth; Torstein Vik; Ann-Mari Brubakk; Torgil Riise Vangberg

doi:10.1016/j.visres.2011.08.002

Visual function and white matter microstructure in very-low-birth-weight (VLBW) adolescents--a DTI study

Susanne Lindqvist, Jon Skranes, Live Eikenes, Olav Haraldseth, Torstein Vik, Ann-Mari Brubakk, Torgil Riise Vangberg

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Premature birth is associated with visual impairments, due to both cerebral and ocular pathology. This study examined the relationship between cerebral white matter microstructure, evaluated by diffusion tensor imaging (DTI), and visual function, in 30 preterm born adolescents with very low birth weight (VLBW=birth weight⩽1500g) and an age-matched group of 45 term born controls. Visual acuity correlated positively with fractional anisotropy (FA) in corpus callosum and in frontal white matter areas in the VLBW participants, but not in the control participants. Callosal visual connections may play a more important role in the development of good visual acuity than previously acknowledged in preterm born children.

Original language	English
Pages (from-to)	2063-70
Number of pages	8
Journal	Vision Research
Volume	51
Issue number	18
DOIs	https://doi.org/10.1016/j.visres.2011.08.002
Publication status	Published - 15 Sep 2011
Externally published	Yes

Keywords

Adolescent
Brain
Diffusion Tensor Imaging
Female
Humans
Infant, Newborn
Infant, Very Low Birth Weight
Male
Regression Analysis
Vision, Ocular
Visual Acuity

Access to Document

10.1016/j.visres.2011.08.002

Cite this

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title = "Visual function and white matter microstructure in very-low-birth-weight (VLBW) adolescents--a DTI study",

abstract = "Premature birth is associated with visual impairments, due to both cerebral and ocular pathology. This study examined the relationship between cerebral white matter microstructure, evaluated by diffusion tensor imaging (DTI), and visual function, in 30 preterm born adolescents with very low birth weight (VLBW=birth weight⩽1500g) and an age-matched group of 45 term born controls. Visual acuity correlated positively with fractional anisotropy (FA) in corpus callosum and in frontal white matter areas in the VLBW participants, but not in the control participants. Callosal visual connections may play a more important role in the development of good visual acuity than previously acknowledged in preterm born children.",

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author = "Susanne Lindqvist and Jon Skranes and Live Eikenes and Olav Haraldseth and Torstein Vik and Ann-Mari Brubakk and Vangberg, {Torgil Riise}",

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AU - Eikenes, Live

AU - Haraldseth, Olav

AU - Vik, Torstein

AU - Brubakk, Ann-Mari

AU - Vangberg, Torgil Riise

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KW - Brain

KW - Diffusion Tensor Imaging

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KW - Infant, Newborn

KW - Infant, Very Low Birth Weight

KW - Male

KW - Regression Analysis

KW - Vision, Ocular

KW - Visual Acuity

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