Abstract
Aim: To investigate the vitamin K status of preterm infants who have a prolonged prothrombin time (PT) in the first month of life. Methods: Measures of vitamin K status were assessed in 21 preterm infants who were found to have an abnormal PT, despite 0.2-0.5 mg vitamin K1 prophylaxis at birth. Results: All infants had normal or supraphysiological vitamin K1 concentrations and undetectable or, in one infant, insignificant PIVKA-II, indicating adequate vitamin K status. Conclusion: In preterm infants born at < 32 wk gestation who received ≥ 0.2 mg vitamin K1 after delivery, a prolonged PT in the first month of life is unlikely to be due to vitamin K deficiency.
Original language | English |
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Pages (from-to) | 1822-1824 |
Number of pages | 3 |
Journal | Acta Paediatrica, International Journal of Paediatrics |
Volume | 94 |
Issue number | 12 |
DOIs | |
Publication status | Published - 1 Dec 2005 |
Externally published | Yes |
Keywords
- Phylloquinone
- PIVKA-II
- Premature