What predicts persistent depression in older adults across Europe? Utility of clinical and neuropsychological predictors from the SHARE study

Damien Gallagher, George Savva, RoseAnne Kenny, Brian A. Lawlor

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    25 Citations (Scopus)

    Abstract

    Background: Depression in later life frequently persists and perpetuating factors are of immediate therapeutic relevance to clinicians. No studies of this scale have examined both clinical and neuropsychological predictors of persistent depression in a cross-national European context. Methods: 4095 community dwelling older adults (=50 yr) with clinically signficant depression (EURO-D=4) from eleven European countries in the Survey of Heath, Ageing, and Retirement in Europe (SHARE) were followed for a median of 28 months. Logistic regression analyses were conducted to determine predictors of persistent depression. Results: 2187 (53.4%) remained depressed at follow up. Independent predictors included: female gender, baseline functional impairment, functional decline, physical symptoms, past history of depression, increased severity of depression, early age of onset (
    Original languageEnglish
    Pages (from-to)192-197
    Number of pages6
    JournalJournal of Affective Disorders
    Volume147
    Issue number1-3
    DOIs
    Publication statusPublished - 1 May 2013

    Keywords

    • Depression
    • Older adults
    • Clinical predictors

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