Whole genome sequencing reveals an outbreak of Salmonella Enteritidis associated with reptile feeder mice in the United Kingdom, 2012-2015

Sanch Kanagarajah, Alison Waldram, Gayle Dolan, Claire Jenkins, Philip M. Ashton, Antonio Isidro Carrion Martin, Robert Davies, Andrew Frost, Timothy J. Dallman, Elizabeth M. De Pinna, Jeremy I. Hawker, Kathie A. Grant, Richard Elson

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Abstract

Analysis of whole genome sequencing data uncovered a previously undetected outbreak of Salmonella Enteritidis that had been on-going for four years. Cases were resident in all countries of the United Kingdom and 40% of the cases were aged less than 11 years old. Initial investigations revealed that 30% of cases reported exposure to pet snakes. A case-control study was designed to test the hypothesis that exposure to reptiles or their feed were risk factors. A robust case-definition, based on the single nucleotide polymorphism (SNP) profile, increased the power of the analytical study. Following univariable and multivariable analysis, exposure to snakes was the only variable independently associated with infection (Odds ratio 810 95% CI (85-7715) p 
Original languageEnglish
Pages (from-to)32-38
Number of pages7
JournalFood Microbiology
Volume71
DOIs
Publication statusPublished - May 2018

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