Whole genome sequencing reveals an outbreak of Salmonella Enteritidis associated with reptile feeder mice in the United Kingdom, 2012-2015

Sanch Kanagarajah; Alison Waldram; Gayle Dolan; Claire Jenkins; Philip M. Ashton; Antonio Isidro Carrion Martin; Robert Davies; Andrew Frost; Timothy J. Dallman; Elizabeth M. De Pinna; Jeremy I. Hawker; Kathie A. Grant; Richard Elson

doi:10.1016/j.fm.2017.04.005

Whole genome sequencing reveals an outbreak of Salmonella Enteritidis associated with reptile feeder mice in the United Kingdom, 2012-2015

Sanch Kanagarajah, Alison Waldram, Gayle Dolan, Claire Jenkins, Philip M. Ashton, Antonio Isidro Carrion Martin, Robert Davies, Andrew Frost, Timothy J. Dallman, Elizabeth M. De Pinna, Jeremy I. Hawker, Kathie A. Grant, Richard Elson

School of Environmental Sciences

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Abstract

Analysis of whole genome sequencing data uncovered a previously undetected outbreak of Salmonella Enteritidis that had been on-going for four years. Cases were resident in all countries of the United Kingdom and 40% of the cases were aged less than 11 years old. Initial investigations revealed that 30% of cases reported exposure to pet snakes. A case-control study was designed to test the hypothesis that exposure to reptiles or their feed were risk factors. A robust case-definition, based on the single nucleotide polymorphism (SNP) profile, increased the power of the analytical study. Following univariable and multivariable analysis, exposure to snakes was the only variable independently associated with infection (Odds ratio 810 95% CI (85-7715) p

Original language	English
Pages (from-to)	32-38
Number of pages	7
Journal	Food Microbiology
Volume	71
DOIs	https://doi.org/10.1016/j.fm.2017.04.005
Publication status	Published - May 2018

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10.1016/j.fm.2017.04.005

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Kanagarajah, S., Waldram, A., Dolan, G., Jenkins, C., Ashton, P. M., Carrion Martin, A. I., Davies, R., Frost, A., Dallman, T. J., De Pinna, E. M., Hawker, J. I., Grant, K. A., & Elson, R. (2018). Whole genome sequencing reveals an outbreak of Salmonella Enteritidis associated with reptile feeder mice in the United Kingdom, 2012-2015. Food Microbiology, 71, 32-38. https://doi.org/10.1016/j.fm.2017.04.005

Kanagarajah, Sanch ; Waldram, Alison ; Dolan, Gayle ; Jenkins, Claire ; Ashton, Philip M. ; Carrion Martin, Antonio Isidro ; Davies, Robert ; Frost, Andrew ; Dallman, Timothy J. ; De Pinna, Elizabeth M. ; Hawker, Jeremy I. ; Grant, Kathie A. ; Elson, Richard. / Whole genome sequencing reveals an outbreak of Salmonella Enteritidis associated with reptile feeder mice in the United Kingdom, 2012-2015. In: Food Microbiology. 2018 ; Vol. 71. pp. 32-38.

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title = "Whole genome sequencing reveals an outbreak of Salmonella Enteritidis associated with reptile feeder mice in the United Kingdom, 2012-2015",

abstract = "Analysis of whole genome sequencing data uncovered a previously undetected outbreak of Salmonella Enteritidis that had been on-going for four years. Cases were resident in all countries of the United Kingdom and 40% of the cases were aged less than 11 years old. Initial investigations revealed that 30% of cases reported exposure to pet snakes. A case-control study was designed to test the hypothesis that exposure to reptiles or their feed were risk factors. A robust case-definition, based on the single nucleotide polymorphism (SNP) profile, increased the power of the analytical study. Following univariable and multivariable analysis, exposure to snakes was the only variable independently associated with infection (Odds ratio 810 95% CI (85-7715) p ",

author = "Sanch Kanagarajah and Alison Waldram and Gayle Dolan and Claire Jenkins and Ashton, {Philip M.} and {Carrion Martin}, {Antonio Isidro} and Robert Davies and Andrew Frost and Dallman, {Timothy J.} and {De Pinna}, {Elizabeth M.} and Hawker, {Jeremy I.} and Grant, {Kathie A.} and Richard Elson",

year = "2018",

month = may,

doi = "10.1016/j.fm.2017.04.005",

language = "English",

volume = "71",

pages = "32--38",

journal = "Food Microbiology",

issn = "0740-0020",

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Kanagarajah, S, Waldram, A, Dolan, G, Jenkins, C, Ashton, PM, Carrion Martin, AI, Davies, R, Frost, A, Dallman, TJ, De Pinna, EM, Hawker, JI, Grant, KA & Elson, R 2018, 'Whole genome sequencing reveals an outbreak of Salmonella Enteritidis associated with reptile feeder mice in the United Kingdom, 2012-2015', Food Microbiology, vol. 71, pp. 32-38. https://doi.org/10.1016/j.fm.2017.04.005

Whole genome sequencing reveals an outbreak of Salmonella Enteritidis associated with reptile feeder mice in the United Kingdom, 2012-2015. / Kanagarajah, Sanch; Waldram, Alison; Dolan, Gayle; Jenkins, Claire; Ashton, Philip M.; Carrion Martin, Antonio Isidro; Davies, Robert; Frost, Andrew; Dallman, Timothy J.; De Pinna, Elizabeth M.; Hawker, Jeremy I.; Grant, Kathie A.; Elson, Richard.

In: Food Microbiology, Vol. 71, 05.2018, p. 32-38.

Research output: Contribution to journal › Article › peer-review

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AU - Grant, Kathie A.

AU - Elson, Richard

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