Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential?

L Nolan; P W M Johnson; A Ganesan; G Packham; S J Crabb

doi:10.1038/sj.bjc.6604557

Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential?

L Nolan, P W M Johnson, A Ganesan, G Packham, S J Crabb

School of Education & Lifelong Learning

Research output: Contribution to journal › Article › peer-review

87 Citations (Scopus)

Abstract

Histone deacetylase inhibitors have progressed rapidly from the laboratory to clinical testing. This review highlights the promising data for their combination with a wide range of established and novel anticancer agents and discusses the mechanisms that underpin these interactions.

Original language	English
Pages (from-to)	689-694
Number of pages	6
Journal	British Journal of Cancer
Volume	99
Issue number	5
DOIs	https://doi.org/10.1038/sj.bjc.6604557
Publication status	Published - 2 Sep 2008

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10.1038/sj.bjc.6604557Licence: CC BY-NC-SA

Cite this

@article{642ba989fdc74973be10b1f00462497d,

title = "Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential?",

abstract = "Histone deacetylase inhibitors have progressed rapidly from the laboratory to clinical testing. This review highlights the promising data for their combination with a wide range of established and novel anticancer agents and discusses the mechanisms that underpin these interactions.",

author = "L Nolan and Johnson, {P W M} and A Ganesan and G Packham and Crabb, {S J}",

year = "2008",

month = sep,

day = "2",

doi = "10.1038/sj.bjc.6604557",

language = "English",

volume = "99",

pages = "689--694",

journal = "British Journal of Cancer",

issn = "0007-0920",