Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential?

L Nolan, P W M Johnson, A Ganesan, G Packham, S J Crabb

Research output: Contribution to journalArticlepeer-review

81 Citations (Scopus)

Abstract

Histone deacetylase inhibitors have progressed rapidly from the laboratory to clinical testing. This review highlights the promising data for their combination with a wide range of established and novel anticancer agents and discusses the mechanisms that underpin these interactions.
Original languageEnglish
Pages (from-to)689-694
Number of pages6
JournalBritish Journal of Cancer
Volume99
Issue number5
DOIs
Publication statusPublished - 2 Sep 2008

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